An observational study of evaluation of extended first trimester screening test to predict early preterm pre-eclampsia in pregnant women

Background: Pre-eclampsia is hypertensive disorder with several complications. Contributes to increased maternal mortality and morbidity. associated pre term labour, IUGR other complications like end organ failure in mother. So, it important diagnose early take appropriate steps mitigate Aim was detect predict preterm pre-eclampsia using extended first trimester screening test pregnant women. Objectives were assess the sensitivity specificity of development pregnancy.Methods: Method used this study observational study.Results: All three parameters, PAPPA, mean arterial pressure (MAP) uterine artery pulsatility index found be significantly predicting preeclampsiaConclusions: This enables us preeclampsia before its clinical presentation. It can as a reliable cost-effective test. will help prevent progression disease by taking necessary timely interventions such ecosprin administration, close frequent follow up screen positive mothers. Thus, useful tool reducing burden fetal morbidity on health system. also has confounding factors due starting prophylactic treatment based ACOG/ NICE guidelines, which false rate.